Shwetha Hara Sridhar

Research and Teaching Assistant, Dr. Allison Johnson.

Virginia Commonwealth University, Virginia 

Aug 2016 – Present

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• Taught the undergraduate level course for Java and Python, BNFO 501. 

• Evaluated and graded examinations, assignments and recorded grades. 

• Led discussion sections, tutorials sections. 

• Developed teaching materials, such as syllabus, answer keys and supplementary notes.

• Informed students of the procedures for completing and submitting class work

• Computer based training software — Blackboard Learn

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Research Assistant, Dr. Peter Uetz's Laboratory.

Virginia Commonwealth University, Virginia 

Aug 2016 – Present

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• Conducted a protein evolutionary comparison assay for 894 distinct bacterial genomes to calculate the essentiality fraction and conservation fraction. 

• Data scraping and cleaning was done by python. R scripting and Tableau was used for data analysis. 

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Data Analyst Intern, Dr. Sherita Chapman at Department of Neurology.

Virginia Commonwealth University Health System, Virginia 

Apr 2017 – Sep 2017

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• Currently, working with creating a design focus group, training research team members and analyzing focus group responses.

• Results were reported in the manuscript for the analysis of prehospital stroke diagnosis by mobile ambulance-based telestroke treatment. 

• Overall, worked with creating a design focus group, training research team members and analyzed focus group responses for inclusion in manuscript.

• The work includes data and statistical analysis to establish codes based on the RE-AIM framework and an inductive approach used to generate themes that emerged from the data. 

• We worked on coding the raw data from each focus group using a question by question coding technique and developed a classification scheme based on key question topics.

• The data was segmented and labeled with a content unit code (a group of words to convey a central meaning), by combining segmented data from each interview and focus group according to the classification scheme. 

• The codes were developed into themes according to the patterns in the data by collaborating with the research team to cross-check and confirm the codes and subsequent themes. 

• The results of the focus groups are being used to develop an implementation plan promoting optimal reach, effectiveness, adoption, implementation, and maintenance of a mobile prehospital telestroke intervention.

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Research Intern, Dr. Glen Kellogg's Laboratory.
Virginia BioTechnology Research Park, Richmond, Virginia

Jan 2017 – May 2017

 

• Wrote the core code to tag each interaction entry in the interaction list files as to its class. Used R to script protein residue interaction maps program.

• Analyzed protein information extracted by separating side chain-side chain, side chain-backbone, and protein-protein interactions.

• Concluded on the outcomes of protein folding, describing the amount of driving force that comes from the side chains vs. backbone conformations.

• Performed the calculations to eventually get the matrices using clustering methods. Coded to tag each interaction entry in the interaction list files as to its class.

Research Assistant
Fortis Healthcare, Bengaluru, India

May 2015 – Jun 2015

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• Diagnostic and analytical procedures performed in the biochemistry, microbiology and the clinical pathology departments.

• Tests performed - hemodialysis, hemofiltration, electron microscopy, diagnosis of a disease by measuring osmolality, high performance liquid chromatography, filtration and deionization to purify water, ion mass spectrometry and biochemistry bodily fluid analysis.

• Instruments used - Cobas-UAII, Millipore Water Purification, Bio-Rad D10 Hemoglobin Testing System, Cryoscopic Osmometer (OSMOMAT 030) and Bio-Rad Lyphochek Tumor Marker Plus Control Levels 1,2 and 3

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Research Assistant
Hetero Drugs Ltd, Hyderabad, India

Jan 2015 – May 2015 

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• During this internship, I assisted and interned in the R&D department.

• Performed biochemical procedures and worked with drug and pharmaceutical productions. This was an opportunity to explore and learn how the major wet lab experiments are done.

• Worked on the formulation and analysis of the anti-retroviral (HIV) drug, Stavudine. Performed procedures to formulate drugs emphasizing on the stage by stage process of making Stavudine and its qualitative analysis.

• Tests and procedures performed - Enzyme-linked immunosorbent assay (ELISA), western blot, immunofluorescence assay (IFA), high-performance thin-layer chromatography (HPTLC), distillation, gas chromatography, particle size analysis and X-Ray diffraction.

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Research Assistant    
DNA LABS INDIA, Hyderabad, India

May 2012 – Aug 2012

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• Worked as an intern with computational tool on drug designing and protein homology modelling, under the guidance of Dr.Manas Ranjan Barik.

• Performed docking studies for ADAM33, a gene causing Asthma.

• Tools and Databases used - Ligand Scout, Acelerys Discovery Studio, NCBI, Uniprot, PDB, Swissprot, BRENDA and KEGG pathway.